Blastocyst Culture

Blastocyst culture

Until about ten years ago, it was impossible to consistently grow (or ‘culture’) embryos in a laboratory to the blastocyst stage. Specialized commercial culture media (the fluid in which embryos are produced in the lab) have now allowed embryos to be successfully nurtured to the blastocyst stage outside of the human body. This is known as ‘blastocyst culture’ in the laboratory.

After the egg retrieval procedure, fertilization is performed in the IVF laboratory using IVF (In-vitro fertilization) or ICSI (intra-cytoplasmic sperm injection), and the resulting embryos are placed in an incubator for the further development. The developmental stages are as follows:

  • The day of egg retrieval is referred to as Day 0. (IVF or ICSI is done after egg retrieval)
  • On the 1 day, the pronuclear stage (embryologist checks as to how many eggs have successfully fertilized)
  • On Day 2, there are two to four cell stages.
  • On day 3, there are eight cells.
  • On day 4, the morula stage
  • On day 5 or 6, the blastocyst stage

Historically, embryo transfer after IVF or ICSI was done on Day 2 or Day 3 after egg collection. However, developments in IVF laboratory technology now allow us to culture embryos for five or six days. This gives the embryos additional chances to demonstrate their developmental potential. Some embryos cease to develop (arrest) before day 5/6. This ‘natural selection’ enables the embryologist to discover and pick the best embryo/embryos for transfer.

Advantages of Blastocyst Culture

Blastocyst culture requires optimal laboratory conditions. Approximately 45% of fertilized eggs reach the blastocyst stage.

Because only the most competent embryos mature to the blastocyst stage, allowing embryos to grow and develop in the laboratory until they reach the blastocyst stage allows for the selection of the most capable embryo/s for embryo transfer.

In addition, in a natural pregnancy, the embryo takes around five days after fertilization to enter the womb, where it subsequently implants. On this day, the uterine lining is very receptive. As a result, blastocyst transfer is more physiological.

Blastocyst culturing is recommended for:

  • For patients with multiple failed IVF: Performing a blastocyst culture on a patient with a history of failed IVF with day2/3 embryo transfer, can yield more information related to the growth of the embryos and aid in improving pregnancy rate
  • To eliminate multiple pregnancies: Blastocyst culture allows the possibility of transferring the single best embryo and thereby reducing the chance of multiple pregnancy.

Contact with SaplingIVF clinic

SaplingIVF Clinic’s friendly and professional team is happy to answer any additional questions you may have regarding whether blastocyst culture and transfer is the right option for you.

What Our Patients Say

Sheetal Jangra
Sheetal Jangra
2023-07-04
Today, after many years, I have got the privilege of becoming a mother only and only because of Dr. Minal madam and for this I would like to thank Minal madam and her extremely supportive staff – thank you for making our life wonderful.
Rajeev Kumar
Rajeev Kumar
2023-07-04
Sapling IVF Center is the best center in Delhi. Dr. Meenal madam and her staff are very cooperative and always available to help their patients - My experience is amazing where we got positive result and we are going to make our dreams come true after few months- thank you Sapling, Meenal mam and her staff...😊
Deepak Rana
Deepak Rana
2023-07-02
Thanks to Dr.Minal mam she is so positive in nature and outstanding in behaviour .Best centre for unlease the happiness.. staff is so supporting . I m so much thankful to mam for arise happiness in my life .
Saurav Singh
Saurav Singh
2023-07-01
Outstanding IVF services at Sapling IVF Delhi center! Their experienced team, cutting-edge technology, and personalized care will made your parenthood journey stress-free and successful. Full of positive vibes, doctor consultation at its best. Highly recommended!
Pradeep Saini
Pradeep Saini
2023-06-30
Very very happy to write review for sapling ivf center .Dr. Minal mam is such a nice person. She is the Best doctor . Her way of talk gives positivity to everyone who visit here and fulfill their hope . This is our first month and we got positive result . Thanks to all mam . Staff also very cooperative, friendly. They are available 24 hours without any hesitation for us. Thank you so much all
radhey ads
radhey ads
2023-06-30
Sapling IVF is one of the best ivf. Centre in delhi. I specially thanks to Minal mam because of her we got our dreams to having parents after 7 years. Dr. Minal is well experienced in her all sites . She is so humble, helpful and clear all things positively with best effort. I also thanks to all staff of centre every member is so polite and helpful. Minal mam thank you so much 😊 for your support
Arti Sharma
Arti Sharma
2023-06-29
When we met Minal Madam for the first time at Sapling, we got a new hope from her confidence, way of explaining and talking. This was our last chance, and it happened exactly as Meenal madam had assured us, I got positive in first go after a failed IUI and IVF at other place. Minal madam's team is very supportive and professional. I have no words to thank Meenal madam and her team. I strongly recommend the couple who have difficulty in conceiving, must visit at Sapling one time...
Sarita Chauhan
Sarita Chauhan
2023-06-29
Super Very very super
Raman Saini
Raman Saini
2023-06-29
No word to say thanks to Minal mam . She is blessing for us . In first IVF we got positive results .Staff is also very lovely , friendly and cooperative . They give always positive vibes to everyone . thanks a lot mam
sharmila Yadav
sharmila Yadav
2023-06-23
This review in best of my purview! My heart filled with joy & happiness,while writing this experience. We(AY & SAY)couple eternally grateful towards Dr. Minal Singh for her expertise in profession with apt guidance, supporting us to walk towards precious gift of life. Awaited great images posting with doctor and babies ! She definitely needs word of mouth and reviews to get better reach and recognition for the work she does with care, precision and passion for her patients. For us she is more like elder sister. She is amazing with her proactiveness, explanations, convincing power. Best way to engage with her is to have open discussion and you can observe the highest suggestions with assurance of success rate. We are and will be always thankful ! Many more happy meetings to discuss progression and advises. Finest recommend place to make there dreams possible with science under precise professional like Dr. Minal, aura and positivity can be sensed at each time you visit. Many Many Thanks Dr Minal. NMRK 🙏
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